PROMPT – Providing Standardized Consented PROMs for Improving Pain Treatment
It’s all about pain treatment. And who knows better about their pain than the patients themselves? Therefore, patient reported outcomes serve as a basis for decisions about pain management. But as many different outcome measurement tools are used to assess treatments, results are difficult to interpret and compare, and it’s not clear which tools work best. This is where PROMPT comes into play.
PROMPT aims at improving management of acute and chronic pain by identifying a core set of PROMs (patient reported outcome measures) that are predictive indicators of treatment success in clinical practice and controlled trials. These will not only address pain intensities as well as the functional consequences of pain for individuals but also identify patients at risk of experiencing chronification of acute post-operative pain. Results will help health care professionals to individualize pain management, and thus improve the quality of life of pain patients.
Within its three work packages, PROMPT will
- define a set of core PROMs which is suitable to assess acute post-operative pain in real world conditions and controlled trials by following existing standards for identifying core outcome sets;
- adopt parts of the established PAIN OUT infrastructure to guarantee smooth routine functioning of PROMPT, and re-allocation of resources to other aspects of the IMI-PainCare project;
- examine whether PROMs validly predict CPSP and mirror treatment responses, or validly assess surgery-specific impairments of physical and cognitive function in chronic pain;
- define a predictor of chronic pain (PCP) which identifies, pre- and post-operatively, patients at risk for CPSP so that they can receive timely primary or secondary prevention measures;
- analyse if remote tracking of patients’ physical activity after surgery is feasible in daily life, and contributes to predict CPSP;
- establish registries for documenting follow-ups after surgery/anaesthesia allowing feed-back in clinical routine months after the patient has left hospital;
- identify PROMs which most reliably predict treatment success in chronic pain in clinical practice and controlled trials in neuropathic and chronic pelvic pain;
- and ultimately, conduct negotiations with EMA to assure that the core set of PROMs will be included into Guidelines for future clinical trials in acute and chronic pain.
The subproject PROMPT is steered by the University of Jena (Germany) and Grunenthal GmbH. You can find all partners of the Consortium participating in this subproject here.